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Publications

Publications in Peer-Reviewed Journals:
*indicates Bates undergraduate student

Sato, J.D., *Ellis, S.B., *Baker, N., *Brackett, D., *Brown, T., *Godek, S.E., *Tolis, D., and Kleckner, N. (2010) Molecular cloning of neuropeptide hormone NPF cDNA from Helisoma trivolvis. Bulletin of the MDI Biological Laboratory, Vol 49: 29-30.

*Scannell, E., *Dell’Ova, C., Quinlan, E., Murphy, A. D., & Kleckner, N. W. (2008) Pharmacology of ionotropic and metabotropic glutamate receptors on neurons involved in feeding behavior in the pond snail, Helisoma trivolvis, J. Exp. Biol., 221: 824-833.

Kelsey, J. E., Mague, S. D., Pijanowski, R. S., Harris, R. C., Kleckner, N. W., & Matthews, R. T. (2004). NMDA receptor antagonists ameliorate the stepping deficits produced by unilateral medial forebrain bundle injections of 6-OHDA in rats. Psychopharmacology 175: 179-88.

Kleckner, N.W., *Glazewski, J.C., *Chen, C.C. and *Moscrip, T.D. (1999) Subtype-selective antagonism of N-methyl-D-aspartate receptors by felbamate: insights into the mechanism of action.J. Pharmacol. Expt. Ther. 289, 886-894.

Kleckner, N. W. and Pallotta, B. S. (1995). Burst kinetics of single NMDA receptors currents in cell-attached patches from rat brain cortical neurons in culture. J. Physiol. 486.2, 411-426.

Eubanks, J. E., Puranum, R., Kleckner, N. W., Bettler, B., Heinemann, S. F., and McNamara, J. O. (1993). The gene encoding the glutamate recptor subunit GluR5 is located on human chromosome 21q21.1-22.1 in the vicinity of the gene for familial amyotrophic lateral sclerosis.PNAS 90, 178-182.

Kleckner, N. W. and Dingledine, R. (1991). Regulation of NMDA receptors by glycine and magnesium during development. Mol. Brain Res., 11, 151-159, 1991.

Kleckner, N. W. and Dingledine, R. (1989). Selectivity of quinoxalines and kynurenines as antagonists of the glycine site on N-methyl-D-aspartate receptors. Mol. Pharmacol., 36, 430-436.

Mc Bain, C. J., Kleckner, N. W., and Dingledine, R. (1989). Structural requirements for activation of the glycine coagonist site on NMDA receptors expressed in Xenopus oocytes. Mol. Pharmacol., 36, 556-565.

Verdoorn, T. A., Kleckner, N. W., and Dingledine, R. (1989). N-methyl-D-aspartate/glycine and quisqualate/ kainate receptors expressed in Xenopus oocytes. Antagonist pharmacology. Mol. Pharmacol., 35, 360-368.

Kleckner, N. W. and Dingledine, R. (1988). Requirement for glycine in activation of N-methyl-D-aspartate receptors expressed in Xenopus oocytes. Science, 241, 835-837.

Verdoorn, T. A., Kleckner, N. W., and Dingledine, R. (1987). Rat brain N-methyl-D-aspartate receptors expressed in Xenopus oocytes. Science, 238,1114-1116.

Kleckner, N. W., Kizaki, Z., and Thurman, R. G. (1987). Potential intercellular futile cycling of carbohydrates in diabetes. Biochem. J., 246, 417-423.

Gray, T. K., Kleckner, N. W., Malloy, P. J., Sivam, G., Dodd, M. C. and Cohen, M. S. (1987). Biological activity of 19-nor, 10-keto, 25-hydroxy vitamin D3. J. Bone Min. Res., 2, 413-419.

Kleckner, N. W. and Sidell, B. D. (1985). Comparison of maximal activities of enzymes from tissues of thermally acclimated and naturally acclimatized chain pickerel (Esox niger). Physiol. Zool. 58, 18-28.

Published Abstracts from Meeting Presentations:

*Gerhold, K., *Knox, A.S., Kleckner, N.W. (2005) Cloning and localization of excitatory glutamate receptors from the central nervous system of Helisoma trivolvis. Soc. Neuroscie. Abstr., in press (Nov. 2005; also presented at the Maine Biomedical Sciences Syposium at MDIBL in May, 2005).

*Rafferty, J.R., and Kleckner, N.W. (2005) Glutamate signal transduction pathways causing inhibition in buccal neurons of Helisoma trivolvis, Soc. Neurosci. Abstr., in press (Nov. 2005; also presented at the Maine Biomedical Sciences Syposium at MDIBL in May, 2005).

Kleckner, N.W., *Percarpio, K. and *Fink, K. (2003) Intracellular signaling pathways linked to glutamate inhibition of neurons involved in feeding behavior in the pond snail, Helisoma trivolvis. Program No. 44.9. 2003 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2003. Online..

Kleckner, N.W., *Mague S., *Pijanowski, R., and Kelsey, J.E. (2001) MK-801 enhances forelimb stepping in the unilateral 6-OHDA-lesioned rat. Soc. Neurosci. Abstr., 27.

Dell’Ova, C.A. and Kleckner, N.W. (2000). Characterization of inhibitory glutamate responses in motor neurons involved in feeding in the pond snail, Helisoma trivolvis. Soc. Neurosci. Abstr., 26, 817.17.

Kleckner, N.W., Kelsey, J., McCormick, C.M. (1999). Undergraduate neuroscience at Bates College: A curriculum based on laboratory science. Soc. Neurosci. Abstr., 25, 264.

McCormick, C.M., Kleckner, N.W., Frye, C. (1999). Testosterone, Dihydrotestosterone, or 3a-androstenediol, but not vehicle, to corticosterone-depleted rats attenuates pyknotic cells in the granule layer of the dentate gyrus. Soc. Neurosci. Abstr., 25, 1448.

*Miller, A., and Kleckner, N.W. (1997). Effects of clozapine and chlorpromazine on the NR1-NR2A and NR1-NR2B subtypes of the N-methyl-D-apsartate (NMDA) receptor expressed in Xenopus oocytes. Soc. Neurosci. Abstr., 23, 919.

*Glazewski, J. C., *Chen, C. C., *Moscrip, T. D. and Kleckner, N. W. (1996). Felbamate inhibition of recombinant N-methyl-D-aspartate receptors expressed in Xenopus oocytes. Soc. Neurosci. Abstr., 22, 1530.

McCormick, C.M., *McNamara, M., Kelsey, J.E. and Kleckner, N.W. (1995). Acute corticosterone replacement three-months after adrenalectomy improves performance in a Morris water maze despite degeneration in the dentate gyrus. Soc. Neurosci. Abstr. , 21, 1944.

Kleckner, N. W. and Pallotta, B. S. (1993). Analysis of open and shut intervals of NMDA-activated ion channels. Biophys. J., 64, A324.

Kleckner, N. W., Cao, Z., Moll, C., Bettler, B., Heinemann, S., and McNamara, J. O. (1992). Increased expression of glutamate receptor mRNAs in human epileptic hippocampus. Soc. Neurosci. Abstr., 18, 90.

Kleckner, N. W. and Dingledine, R. (1990). Developmental regulation of NMDA receptors by magnesium and glycine. Soc. Neurosci. Abstr., 16, 619.

Kleckner, N. W. and Dingledine, R. (1989). Similarity between quisqualate receptors and the glycine site on NMDA receptors: Evidence from antagonist pharmacology. Soc. Neurosci. Abstr., 15, 325.

Kleckner, N. W. and Dingledine, R. (1989). Halogenated quinoxalines and kynurenines as antagonists of the glycine site on N-methyl-D-aspartate receptors. Eur. J. Neurosci. Suppl. 2, 94.

McBain, C. J., Kleckner, N. W., and Dingledine, R. (1989). Structural requirements of glycine site agonists for activation of NMDA receptorss in Xenopus oocytes. Eur. J. Neurosci. Suppl. 2, 102.

Kleckner, N. W. and Dingledine, R. (1988). Glycine requirement for activation of N-methyl-D-aspartate receptors in Xenopus oocytes. Soc. Neurosci. Abstr., 14, 236.

Kleckner, N. W., Verdoorn, T. A., and Dingledine, R. (1987). NMDA receptors expressed in Xenopus oocytes are regulated by Mg and glycine. Soc. Neurosci. Abstr., 13, 752.

Kleckner, N. W., Kizaki, K., and Thurman, R. G. (1986). Gluconeogenesis occurs exclusively in periportal (PP) regions of the liver lobule in perfused livers from diabetic rats. The Pharmacologist, 28, 575(abstr.).


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