Lori Banks – Microbiology

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Research Interests

During my sophomore year of college, the Ameri-thrax attacks and other subsequent bioterrorism threats changed the tone and focus of my study of biology and chemistry. I discovered that the key to fighting bioterrorism, antibiotic resistance, and epidemic, infectious diseases, all centered on a molecular understanding of host-pathogen interactions. After years in the research lab, I have come to understand that the interactions of molecules drive lots of other kinds of disease as well. Identifying and characterizing the most important of these interactions gives us the starting point for most drug design, and a chance to create new medicine. The focus of the Banks Lab is to understand the key structural features of selected microbial proteins that can be exploited in the design of new anti-microbial agents.

ORCIDhttps://orcid.org/0000-0003-4684-8763

LinkedIn:  https://www.linkedin.com/in/lori-banks-4915037/

Maine INBREhttps://inbre.maineidea.net/research-projects/epigenetic-mechanisms-of-memory-formation-and-maintenance-2-2-2-2/

Selected Publications

Adamski, C.J., Cardenas, A.M., Brown, N.G., Horton,L.B., Sankaran, B., Prasad, B.V.V., Gilbert, H.F., and T. Palzkill. 2014. Molecular basis for the catalytic specificity of the CTX-M extended-spectrum beta-lactamases. Biochemistry 54(2):447-457.
DOI: 10.1021/bi501195g

Sastri, N.P., Viskovska, M., Hyser, J.M., Tanner, M.R., Horton, L.B., Sankaran, B., Prasad, B.V.V., and M.K. Estes. 2014. Structural plasticity of the coiled-coil domain of rotavirus NSP4. J. Virology 88(23):13602-13612.
DOI: 10.1128/JVI.02227-14

Chen, P., Horton, L.B., Mikulski, R.L., Deng, L., Sundriyal, S.,  Palzkill, T., and Y. Song. 2012. 2-Substituted 4,5-dihydrothiazole-4-carboxylic acids are novel inhibitors of metallo-beta-lactamases. Bioorganic & Medicinal Chemistry Letters 22(19):6229-6232.
DOI: 10.1016/j.bmcl.2012.08.012

Contact:

Lori Banks, PhD
Assistant Professor of Biology

Bates College
44 Campus Ave
Lewiston, ME 04240
LBanks@bates.edu
207-786-6108