{"id":10,"date":"2020-02-10T19:11:57","date_gmt":"2020-02-10T19:11:57","guid":{"rendered":"https:\/\/www.bates.edu\/biosafety\/?page_id=10"},"modified":"2020-02-10T20:27:08","modified_gmt":"2020-02-10T20:27:08","slug":"what-is-biosafety-research","status":"publish","type":"page","link":"https:\/\/www.bates.edu\/biosafety\/what-is-biosafety-research\/","title":{"rendered":"What is Biosafety Research"},"content":{"rendered":"\n<p>Biosafety level 2 organisms or cells or tissues, (including most human, non-human primate, or other mammalian cells) at Bates College requires approval of the Institutional Biosafety Committee. Work with Biosafety Level 3 or 4 organisms is not permitted on campus. If you are uncertain about the classification of the organisms you are working with, please check the following database: <\/p>\n\n\n\n<p><a href=\"https:\/\/my.absa.org\/tiki-index.php?page=Riskgroups&amp;default%5Bcontent%5D=ascaris\">https:\/\/my.absa.org\/tiki-index.php?page=Riskgroups&amp;default%5Bcontent%5D=ascaris<\/a><\/p>\n\n\n\n<p>Work with recombinant DNA also requires approval from the Institutional Biosafety Committee.&nbsp;<strong>Even rDNA work that is exempt is expected to have an official \u201cExempt\u201d letter.<\/strong>&nbsp; Please&nbsp;<strong><a href=\"https:\/\/www.bates.edu\/biosafety\/files\/2020\/02\/biosafety-flow-chart_bates.pdf\">consult this flowchart<\/a><\/strong>&nbsp;to aid with differentiating between exempt and non-exempt experiments. &nbsp;The ONLY rDNA experiments that are exempt from review are rDNA molecules that are not in organisms or viruses or:<\/p>\n\n\n\n<p>VIII\u2011F\u20112&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;rDNA molecules that consist entirely of DNA segments from a&nbsp;single nonchromosomal     or viral DNA source, though one or more of the segments may be a synthetic equivalent.<\/p>\n\n\n\n<p>VIII\u2011F\u20113&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;rDNA molecules that consist entirely of DNA from a prokaryotic host including its indigenous plasmids or viruses when propagated only in that host (or a closely related strain of the same species), or when transferred to another host by well-established physiological means.<\/p>\n\n\n\n<p>VIII\u2011F-4&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;rDNA molecules that consist entirely of DNA from a eukaryotic host including its chloroplasts, mitochondria, or plasmids (but excluding viruses) when propagated only in that host (or closely related strain of the same species).<\/p>\n\n\n\n<p>VIII\u2011F\u20115&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;rDNA molecules that consist entirely of DNA segments from different species that exchange DNA by known physiological processes, though one or more of the segments may be a synthetic equivalent.<\/p>\n\n\n\n<p>VIII\u2011F\u20116&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;rDNA experiments that do not present a significant risk to health or the environment as determined by&nbsp;the NIH Director, RAC and following appropriate notice and opportunity for public comment.<\/p>\n\n\n\n<p><br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Biosafety level 2 organisms or cells or tissues, (including most human, non-human&hellip;<\/p>\n","protected":false},"author":5,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_hide_ai_chatbot":false,"_ai_chatbot_style":"","associated_faculty":[],"_Page_Specific_Css":"","_bates_restrict_mod":false,"_dimp_site_id":"","_dimp_override_contact":false,"_table_of_contents_display":false,"_table_of_contents_location":"","_table_of_contents_disableSticky":false,"_is_featured":false,"footnotes":"","_bates_seo_meta_description":"","_bates_seo_block_robots":false,"_bates_seo_sharing_image_id":0,"_bates_seo_sharing_image_twitter_id":0,"_bates_seo_share_title":"","_bates_seo_canonical_overwrite":"","_bates_seo_twitter_template":""},"class_list":["post-10","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.bates.edu\/biosafety\/wp-json\/wp\/v2\/pages\/10","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.bates.edu\/biosafety\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bates.edu\/biosafety\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bates.edu\/biosafety\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bates.edu\/biosafety\/wp-json\/wp\/v2\/comments?post=10"}],"version-history":[{"count":2,"href":"https:\/\/www.bates.edu\/biosafety\/wp-json\/wp\/v2\/pages\/10\/revisions"}],"predecessor-version":[{"id":44,"href":"https:\/\/www.bates.edu\/biosafety\/wp-json\/wp\/v2\/pages\/10\/revisions\/44"}],"wp:attachment":[{"href":"https:\/\/www.bates.edu\/biosafety\/wp-json\/wp\/v2\/media?parent=10"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}