{"id":33642,"date":"2004-03-22T10:02:13","date_gmt":"2004-03-22T14:02:13","guid":{"rendered":"http:\/\/home.bates.edu\/?p=33642"},"modified":"2016-02-04T15:53:30","modified_gmt":"2016-02-04T20:53:30","slug":"biochemist-grant","status":"publish","type":"post","link":"https:\/\/www.bates.edu\/news\/2004\/03\/22\/biochemist-grant\/","title":{"rendered":"Bates biochemist receives $272,000 grant"},"content":{"rendered":"<div>\n<p><a href='https:\/\/www.bates.edu\/news\/files\/2004\/03\/schlax72.jpg'><img loading=\"lazy\" decoding=\"async\" width=\"120\" height=\"169\" src=\"https:\/\/www.bates.edu\/news\/files\/2004\/03\/schlax72.jpg\" class=\"attachment-medium alignleft\" alt=\"schlax72\" \/><\/a><\/p>\n<p>Paula Schlax, an assistant professor of chemistry at Bates College, has received a National Science Foundation grant for nearly $272,000 to support her research into bacterial responses to environmental stress.<\/p>\n<p>This research, in which Schlax closely involves her students, promises to increase understanding of fundamental principles that govern whether or not genes express biologically active proteins.<\/p>\n<p><!--more--><\/p>\n<p>Schlax, of Lewiston, will receive $271,840 from the NSF over three years. A member of the Bates faculty since 1998, she is investigating mechanisms through which bacteria respond to changes in their immediate environment.<\/p>\n<p>Specifically, Schlax studies a molecule called RpoS that is common to many bacteria and regulates their stress response. Environmental stresses such as extreme temperatures, acidity or salinity trip a &#8220;genetic switch&#8221; that results in high RpoS levels. This stimulates the creation of &#8220;protector molecules&#8221; that toughen the organism against many types of stresses.<\/p>\n<p>Understanding the stress response helps explain how bacteria survive drastic changes in their natural environment and how environmental stresses influence the composition of bacterial species in a natural ecosystem.<\/p>\n<p>Additionally, many disease-causing bacteria undergo this stress response, says Schlax, and that response can influence organisms&#8217; ability to harm human hosts. Understanding this process may provide insight into the mechanisms by which these organisms cause disease.<\/p>\n<p>The NSF award is especially gratifying, Schlax says, because it &#8220;recognizes that Bates undergraduate students will participate in increasing fundamental scientific knowledge. It&#8217;s a great compliment to our students.&#8221;<\/p>\n<p>She says, &#8220;Students will participate in all aspects of this research, from designing and carrying out experiments to interpreting data and presenting it to the greater scientific community.&#8221;<\/p>\n<p>This work crosses the traditional boundaries of chemistry and molecular biology by investigating the relationship between the structure of RNA molecules and their function in gene expression, Schlax says. A goal is to &#8220;map&#8221; gene expression networks, which is a small part of the cutting-edge discipline of functional genomics.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Paula Schlax, an assistant professor of chemistry at Bates College, has received a National Science Foundation grant for nearly $272,000 to support her research into bacterial responses to environmental stress.<\/p>\n","protected":false},"author":148,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_hide_ai_chatbot":false,"_ai_chatbot_style":"","associated_faculty":[],"_Page_Specific_Css":"","_bates_restrict_mod":false,"_table_of_contents_display":false,"_table_of_contents_location":"","_table_of_contents_disableSticky":false,"_is_featured":false,"footnotes":"","_bates_seo_meta_description":"","_bates_seo_block_robots":false,"_bates_seo_sharing_image_id":0,"_bates_seo_sharing_image_twitter_id":0,"_bates_seo_share_title":"","_bates_seo_canonical_overwrite":"","_bates_seo_twitter_template":""},"categories":[4,11011,39,217],"tags":[97,10763,6283,6842],"class_list":["post-33642","post","type-post","status-publish","format-standard","hentry","category-academic-life","category-awards","category-event-highlights","category-science-technology","tag-awards-to-faculty","tag-chemistry","tag-national-science-foundation","tag-paula-schlax"],"_links":{"self":[{"href":"https:\/\/www.bates.edu\/news\/wp-json\/wp\/v2\/posts\/33642","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.bates.edu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bates.edu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bates.edu\/news\/wp-json\/wp\/v2\/users\/148"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bates.edu\/news\/wp-json\/wp\/v2\/comments?post=33642"}],"version-history":[{"count":2,"href":"https:\/\/www.bates.edu\/news\/wp-json\/wp\/v2\/posts\/33642\/revisions"}],"predecessor-version":[{"id":90749,"href":"https:\/\/www.bates.edu\/news\/wp-json\/wp\/v2\/posts\/33642\/revisions\/90749"}],"wp:attachment":[{"href":"https:\/\/www.bates.edu\/news\/wp-json\/wp\/v2\/media?parent=33642"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bates.edu\/news\/wp-json\/wp\/v2\/categories?post=33642"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bates.edu\/news\/wp-json\/wp\/v2\/tags?post=33642"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}